Polynucleotides
A regenerative skin treatment, often used around the eyes and neck.

Polynucleotides are injectable treatments derived from purified DNA fragments, used as part of a skin treatment plan.
They're usually given as a short course, discussed with you in advance after an assessment of your skin.
Depending on your goals, Rebeca may suggest combining it with skin boosters or RF microneedling as part of a wider plan.
Polynucleotide treatments
One syringe in one session, usually as part of a course for the face, eyes or neck.
Polynucleotides for the backs of the hands. See hand rejuvenation.
Polynucleotides for the scalp. See hair restoration.
What polynucleotides are
Polynucleotides are chains of DNA fragments, highly purified from salmon or trout, that are injected in small amounts into the skin. They support the skin's own repair processes and help improve hydration, thickness and elasticity over time.
They don't add volume and won't change your features. Changes are gradual, so they suit people who want healthier-looking skin rather than an obvious difference.
Where they're used
Under the eyes, where skin is thin and shows crepiness and dark circles early. There are products designed specifically for this delicate area.
Across the face, neck and décolletage to improve overall skin quality, and on the backs of the hands. They're also used on the scalp as part of hair restoration.
The course
A typical course is three or four sessions, two to three weeks apart, with maintenance sessions after that. Mild redness, small bumps and occasional bruising settle within a day or two; the under-eye area can swell a little more.
Honest advice, and knowing when to say, “You don't need that.”
Rebeca Lydiatt · RGN, Nurse Prescriber
How it works
Your goals, history and questions first.
Rebeca explains options, cost and timings.
Around 45 min, only what you need.
Aftercare to follow and a review if needed.
Is it right for you?
- Not offered to anyone under 18.
- Not offered during pregnancy or breastfeeding.
- Not offered where there's an active infection or skin condition at the treatment site.
- Common: small raised bumps at injection points, redness, tenderness and bruising, usually settling quickly.
- Less common: lumps or nodules, particularly with collagen-stimulating treatments, and infection.
- Your medical history is checked first to reduce the chance of a reaction.
Results vary from person to person. Everything is explained before you consent, and you can take time to decide.
Good to know
Is it the same as filler?
No. These treatments are spread across an area to improve the skin itself, not to add volume, so the shape of your face doesn't change.
How many sessions will I need?
They're usually given as a short course. The number of sessions and the gap between them are agreed with you at consultation.
Is there downtime?
Small bumps at the injection points and some redness are common and usually settle quickly. Bruising is possible.
Does it hurt?
Numbing cream is applied first. Most people find it very manageable.
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Questions about polynucleotides?
Leave your details and Rebeca will get back to you, usually the same working day.
“Very refreshing to have expert advice in a clear, non-pushy way.”


